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Krill Oil Beats Fish Oil Omega-3s In Battling Metabolic Dysfunctions
“Omega-3s sourced from krill are more effective than fish oil in combating some metabolic symptoms including raised fat levels in the heart and liver and violent mood swings in obese individuals, according to Italian researchers.”
A study published in the Journal of Nutrition concludes that both conventional fish oil and krill oil are effective in reducing fat levels, but that krill oil is more effective.
The mechanisms of why this was the case had not been made clear in the study, but suggested that long-chain polyunsaturated fatty acids may reduce activity in the endocannabinoid system.
The endocannabinoid system sounds complicated and hard to pronounce, but it consists of a group of neuromodulatory lipids and receptors that influence your appetite, pain sensation, mood and memory.
Here is a quote from the study: “Whereas CB1 (cannabinoid receptor type 1) receptor antagonists dampen the overactivated endocannabionid system by blocking the receptor, dietary (n-3) LCPUFA, and KO (krill oil) in particular, may reduce the activity of the endocannabinoid system by decreasing the substrate availability for endocannabinoid biosynthesis,” the researchers said. “Such a nutritional approach, if influencing the endocannabinoid system only peripherally, might avoid the adverse psychiatric effects associated with the use of CB1 antagonists, thus potentially providing a safer alternative for ‘endocannabinoid reequilibration’ in obese individuals.”
The researchers found that when parameters that were associated with obesity were considered the krill oil reduced rats heart fat levels by 42% compared to 2% for conventional fish oils.
A 60% reduction in liver fat was also observed for krill oil supplementation compared to only 38% for fish oil supplementation. Not only is the reduction significant it is just as important to note that fat build up in the liver can lead to insulin insensitivity and cause type-2 diabetes.
Researchers stated: “It is worth noting that in all tissues exhibiting changes in endocannabinoid concentrations, EPA and DHA concentrations in the PL (phospholipid) fraction were increased and the increase was greater in the Krill Oil compared with fish oil-supplemented rats.”
Now even though this study was done with rats the results are very significant and generally do carry over to human studies. Since Krill Oil has been deemed through research safe and effective with increasing your EPA and DHA levels we would expect Krill Oil to also reduce the fat levels in your heart and liver of obese and overweight individuals.
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“Endocannabinoids May Mediate the Ability of (n-3) Fatty Acids to Reduce Ectopic Fat and Inflammatory Mediators in Obese Zucker Rats”
Authors: Barbara Batetta, Mikko Griinari, Gianfranca Carta, Elisabetta Murru, Alessia Ligresti, Lina Cordeddu, Elena Giordano, Francesca Sanna, Tiziana Bisogno, Sabrina Uda, Maria Collu, Inge Bruheim, Vincenzo Di Marzo and Sebastiano Banni.
Source: Journal of Nutrition (August, 2009)
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